Transcriptional regulation of adaptive NK and CD8 T cell responses [RNA-Seq]

ABSTRACT: Natural killer (NK) cells are innate lymphocytes that possess features of adaptive immunity such as clonal expansion and generation of long-lived memory. Here we look at transcriptional profiles of NK cells throughout several time points during MCMV infection, ex-vivo cytokine stimulation, and/or deficiency of key transcription factors such as STAT4, STAT1, and Runx1. In addition, we profile parallel time points of MCMV-specific CD8 T cells during infection and memory formation.

ORGANISM(S): Mus musculus

PROVIDER: GSE106138 | GEO | 2017/12/20

SECONDARY ACCESSION(S): PRJNA415721

REPOSITORIES: GEO