Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes

ABSTRACT: To gain into the molecular mechanisms and pathways involved in doxorubicin induced cardiotoxicity, we performed whole genome transcriptome profiling via RNA-seq in hESCs-derived CMs treated with doxorubicin or vehicle only control. Cells were treated with 0, 1 or 2.5 μM of doxorubicin for 16 hours and RNA was isolated for high throughput sequencing

ORGANISM(S): Homo sapiens

PROVIDER: GSE106297 | GEO | 2018/02/21

REPOSITORIES: GEO