Identification of Driver Mutations for Induction of Pancreatic Cancer from Adult Tree Shrew (Tupaia belangeri chinensis) Acinar Cells

ABSTRACT: To investigate gene expression in the tree shrew pancreatic cancer model, tumor samples were analyzed by RNA-seq and the expression profiles were compared to those of human pancreatic cancer samples (n = 30) containing KRAS, TP53, and CDKN2A/B mutations downloaded from The Cancer Genome Atlas (https://tcga-data.nci.nih.gov/) and mouse pancreatic cancer (accession no. GSE87388), which showed similar histological features

ORGANISM(S): Tupaia chinensis

PROVIDER: GSE106343 | GEO | 2018/10/30

REPOSITORIES: GEO