Transcript analysis of CD45+Ter119+CD71+ erythroid-like progenitor cells from tumor-bearing mice

ABSTRACT: We report the application of RNA sequencing technology for high-throughput profiling of transcriptome in mammalian cells. By this method, we report that the CD45+ EPC transcriptome resembled that of MDSCs. Mechanistically, like MDSCs, production of reactive oxygen species is a major mechanism for EPC-mediated immunosuppression.

ORGANISM(S): Mus musculus

PROVIDER: GSE106384 | GEO | 2018/10/29

REPOSITORIES: GEO