Amyotrophic Lateral Sclerosis associated FUS mutation shortens mitochondria and induces neurotoxicity

ABSTRACT: We employ CLIP-Seq, RNA-Seq and Ribo-Seq in cultured neurons expressing R495X or wild-type FUS to identify effects of the mutation on the FUS targetome and on the neuronal transcriptome at the expression and translation level

ORGANISM(S): Mus musculus

PROVIDER: GSE106386 | GEO | 2017/11/01

SECONDARY ACCESSION(S): PRJNA416661

REPOSITORIES: GEO