RNAseq anaysis of ventral striatum cholinergic cells of p11 cKO mice

ABSTRACT: Purpose: To identify gene expression changes in cholinergic neurons of the ventral striatum of p11 cKO mice Method: Translating Ribosome Affinity Purification (TRAP) to isolate RNA from ChAT+ cells and, cDNA synthesisi and next generation RNAseq using Illumina Hiseq sequencer. Results: Biostatistical analysis identified 113 genes that were altered by p11. 59 genes were up-regulated and 54 down-regulated.

ORGANISM(S): Mus musculus

PROVIDER: GSE106389 | GEO | 2018/11/01

REPOSITORIES: GEO