Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies

ABSTRACT: Cell lines derived from NK cell neoplasms were characterized using RNA sequencing and high-throughput drug sensitivity profiling to identify therapeutically actionable drivers in malignant NK cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE106391 | GEO | 2017/11/10

SECONDARY ACCESSION(S): PRJNA416701

REPOSITORIES: GEO