Cellular and molecular basis of increased renal ammonia excretion in hyperammonemic conditions

ABSTRACT: First, to characterize experimentally the changes in metabolic processes and gene expression associated with systemic hyperammonemia, in order to better understand the mechanisms responsible for this pathology; second, to construct a predictive a metabolic model of the pathways involved in order to investigate how the development of hyperammonemia can be explained by fundamental shifts in cellular metabolic objectives and gene expression.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE106682 | GEO | 2020/08/01

REPOSITORIES: GEO