Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma

ABSTRACT: By genome-wide ChIP-seq analysis in ABC DLBCL cell lines, we identified 2,251 STAT3 direct target genes, which involve B cell activation, survival, proliferation, differentiation and migration. Whole transcriptome profiling revealed that STAT3 acts as both a transcriptional activator and suppressor.

ORGANISM(S): Homo sapiens

PROVIDER: GSE106844 | GEO | 2018/01/01

SECONDARY ACCESSION(S): PRJNA418173

REPOSITORIES: GEO