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Gene expression dynamics of Flt3L induced ex vivo BMDC differentiation

ABSTRACT: To understand the gene expression dynamics during Flt3L induced Bone-marrow derived dendritic cell (BMDC) differentatiion we performed RNA-seq. Three distinct stages were chosen and included the initial bone marrow cells, the Common Myeloid Progenitor (CMP), and fully differentiated BMDC.

ORGANISM(S): Mus musculus

PROVIDER: GSE107026 | GEO | 2023/11/06

REPOSITORIES: GEO

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DNA methylation dynamics of Flt3L induced ex vivo BMDC differentiation

Project description:To understand the DNA methylation dynamics during Flt3L induced Bone-marrow derived dendritic cell (BMDC) differentatiion we performed reduced representation bisulfite sequencing (RRBS). Three distinct stages were chosen and included the initial bone marrow cells, the Common Myeloid Progenitor (CMP), and fully differentiated BMDC.

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Project description:We compared the expression profiles of bone marrow-derived dendritic cells (BMDC) derived from Arc/Arg3.1 knockout and wildtype animals. We generated bone marrow-derived dendritic cells (BMDC) from Arc/Arg3.1 knockout and wildtype animals. BMDC were either stimulated with LPS or left untreated and analysed by microarray.

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Gene profiling in CBA and BL/6 bone marrow derived dendritic cells (BMDC)

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DNA methylation and transcriptome dynamics of Flt3L induced ex vivo BMDC differentiation

Project description:This SuperSeries is composed of the SubSeries listed below.

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2014-02-25 | E-GEOD-55307 | biostudies-arrayexpress

Gene epxression profiling in murine bone marrow Lin- cells transduced with BCR-ABL and/or IRF8 followed by Flt3L culture for 5 days

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