Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2500 (Mus musculus)
SUBMITTER: yiping fan
PROVIDER: GSE107150 | GEO | 2017-12-16
SECONDARY ACCESSION(S): PRJNA419196
REPOSITORIES: GEO
Nature 20171213 7685
Memory CD8 T cells that circulate in the blood and are present in lymphoid organs are an essential component of long-lived T cell immunity. These memory CD8 T cells remain poised to rapidly elaborate effector functions upon re-exposure to pathogens, but also have many properties in common with naive cells, including pluripotency and the ability to migrate to the lymph nodes and spleen. Thus, memory cells embody features of both naive and effector cells, fuelling a long-standing debate centred on ...[more]