Alteration of treatment of the ALK inhibitor in ALK-amplified neuroblastoma

ABSTRACT: Anaplastic Lymphoma Kinase (ALK) most frequently mutated in neuroblastoma (NB) and is atractive molecular target for therapy. However, efficacy of the ALK inhibitor against ALK-amplified NB is unclear. To elucidate genetic alterations induced by treatment of the ALK inhibitor, we compared expression profile between ALK inhibitor-treated and DMSO-treated NB39nu cells using Agilent SurePrint G3 Human GE 8x60K V2 Microarray Kit

ORGANISM(S): Homo sapiens

PROVIDER: GSE107354 | GEO | 2017/11/28

SECONDARY ACCESSION(S): PRJNA419884

REPOSITORIES: GEO