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Chromatin landscapes in mouse haploid stem cells [RRBS-seq]

ABSTRACT: We generate histone modification profiles and DNA methylation profiles of mouse haploid embryonic stem cells. By comparison to mouse diploid ESCs and MEFs, we found the similar chromatin landscapes between haESCs and mESCs, which reveal the self-renew ability and pluripotency in haESCs. Besides, haESCs specific chromatin landscapes show its sperm-like functions.

ORGANISM(S): Mus musculus

PROVIDER: GSE107359 | GEO | 2018/03/07

REPOSITORIES: GEO

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Chromatin landscapes in mouse haploid stem cells [ChIP-seq]

Project description:We generate histone modification profiles and DNA methylation profiles of mouse haploid embryonic stem cells. By comparison to mouse diploid ESCs and MEFs, we found the similar chromatin landscapes between haESCs and mESCs, which reveal the self-renew ability and pluripotency in haESCs. Besides, haESCs specific chromatin landscapes show its sperm-like functions.

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