Gene expression in murine embryonic fibroblasts stimulated with DNA or LPS

ABSTRACT: MyD88 may play a direct role in STING-dependent signaling, or alternatively that STING-dependent pro-inflammatory cytokines may require downstream MyD88-dependent signaling to exert their effect. To determine this, we treated STING or MyD88-deficient murine embryonic fibroblasts (MEFs), bone marrow derived macrophages (BMDM) or dendritic cells (BMDC) with exogenous CDN’s or cytosolic dsDNA (ISD) which triggers STING-signaling and type I IFN production.

OTHER RELATED OMICS DATASETS IN: PRJNA421451 PRJNA421452 PRJNA421445

ORGANISM(S): Mus musculus

PROVIDER: GSE107809 | GEO | 2018/02/01

REPOSITORIES: GEO