PBMC gene expression from Crohn's disease patients before Infliximab therapy.

ABSTRACT: About 40% IBD patients treated with anti-TNF antibodies do not respond to therapy. Baseline biomarkers of response are therefore of interest. By combining computational deconvolution of gene expression and meta-analysis approaches we identified cellular biomarkers in tissue (validated in 2 cohorts by IHC of biopsies), and investigated associated gene biomarkers in blood. This dataset provides data from the validation cohort III (blood).

ORGANISM(S): Homo sapiens

PROVIDER: GSE107865 | GEO | 2018/02/01

REPOSITORIES: GEO