Role of SRF in activity-regulated transcription in the striatum of the brain

ABSTRACT: Ablation of the Srf gene in dopaminoceptive neurons of the brain was performed using the Cre/loxP system, with the recombinase expressed from a BAC-derived Drd1a promoter. Our goal was to analyze how loss of SRF will affect acitivity-regulated transcription induced by strong stimulation, i.e. cocaine. Keywords: Treatment x Genotype

ORGANISM(S): Mus musculus

PROVIDER: GSE10870 | GEO | 2009/04/30

SECONDARY ACCESSION(S): PRJNA107375

REPOSITORIES: GEO