Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance

ABSTRACT: To establish a data-driven learning model of the temporal dynamics and 3D chromatin reorganization, we conducted tethered chromatin conformation (TCC) sequencing to examine 3D structure dynamics in estradiol (E2)-induced breast cancer MCF7 cells and Tamoxifen resistant breast cancer MCF7 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE108787 | GEO | 2019/04/09

REPOSITORIES: GEO