Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells

ABSTRACT: RNA-seq: Gene expression profiling in MCF-7 cells treated with vehicle (0), estradiol (E2), the Selective ER Modulator 4-hydroxytamoxifen (OHT), or the pure antiestrogen fulvestrant (ICI). ChIP-seq: Genome-wide DNA binding profile of ERα and SUMO2/3 in MCF-7 cells treated with vehicle, E2 or ICI.

ORGANISM(S): Homo sapiens

PROVIDER: GSE108883 | GEO | 2018/01/09

SECONDARY ACCESSION(S): PRJNA429003

REPOSITORIES: GEO