Next-generation sequencing of human dermal fibroblasts transdifferentiated towards the otic lineage

ABSTRACT: We report the RNAseq analysis of human dermal fibroblasts which have been treated by protocols to stimulate their differentiation towards the otic lineage. This was achieved by transfection with different transcription factors with the aim to induce an initial reprogramming of the cells and was followed by growth factor treatments known to promote otic differentiation. The results show that a partial differentiation towards the otic lineage is achieved by these protocols.

ORGANISM(S): Homo sapiens

PROVIDER: GSE108905 | GEO | 2018/01/09

SECONDARY ACCESSION(S): PRJNA429064

REPOSITORIES: GEO