NUP98/HHEX a new oncogenic fusion with acute myeloid leukemia

ABSTRACT: We have cloned and characterized a fusion gene NUP98/HHEX1 resulting from t(7;10) from a patient with acute myeloid leukemia (AML). As NUP98/HHEX acts as an aberrant transcriptional activator, putative targets were searched upon transient expression of the fusion in primary murine bone marrow cells. Keywords: Comparative analysis of NUP98/HHEX, NUP98/HOX vs. MIG (empty virus) in primary bone marrow cells

ORGANISM(S): Mus musculus

PROVIDER: GSE10909 | GEO | 2008/04/01

SECONDARY ACCESSION(S): PRJNA107201

REPOSITORIES: GEO