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Microarrays analysis of SREBP-1a and SREBP-1c target genes identify new regulatory pathways.

ABSTRACT: In this study we have identified the target genes of SREBP1a and SREBP1c in primary cultures of human skeletal muscle cells using adenoviral vectors expressing the mature nuclear form of human SREBP1a or SREBP1c combined with oligonucleotide microarrays. Keywords: comparison of human myotubes infected either by SREBP1a or 1C

ORGANISM(S): Homo sapiens

PROVIDER: GSE10918 | GEO | 2008/06/19

SECONDARY ACCESSION(S): PRJNA107219

REPOSITORIES: GEO

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Microarrays analysis of SREBP-1a and SREBP-1c target genes identify new regulatory pathways.

Project description:In this study we have identified the target genes of SREBP1a and SREBP1c in primary cultures of human skeletal muscle cells using adenoviral vectors expressing the mature nuclear form of human SREBP1a or SREBP1c combined with oligonucleotide microarrays. Keywords: comparison of human myotubes infected either by SREBP1a or 1C Human myotubes were prepared from 3 different skeletal muscle biopsies. After 7 days of differentiation, myotubes were infected for 48 hours with recombinant adenovirus expressing either Renilla, nuclear SREBP1a or nuclear SREBP1c. Each SREBP1a or SREBP1c infected myotubes culture was compared to Renilla infected myotubes culture. Renilla infected myotubes were considered as the control. Three biological replicates were processed.

2010-05-26 | E-GEOD-10918 | biostudies-arrayexpress

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RNA-Seq of Ewing sarcoma shA673-1c cells

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Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling [SREBP]

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Expression data from 10 months old sciatic nerves of Sterol regulatory element binding factor 1c (SREBF-1c) KO mice and relative littermates

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