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MiRNA expression data from human PBMC derived form acute infectious mononucleosis patients

ABSTRACT: Epstein Barr virus (EBV) is the etiological agent of acute infectious mononucleosis (IM). Since acute IM is a self-resolving disease with most patients regaining health in one to three weeks there have been few studies examining molecular signatures in early acute stages of the disease. microRNAs have been shown, however, to influence immune cell function and consequently the generation of antibody responses in IM. In this study, we performed a comprehensive analysis of differentially expressed microRNAs in early stage uncomplicated acute IM. We used microarrays to profile microRNAs from patient peripheral blood obtained at the time of IM diagnosis and at subsequent time points, and identified differentially regulated microRNAs in this process.

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE109220 | GEO | 2018/01/17

SECONDARY ACCESSION(S): PRJNA430181

REPOSITORIES: GEO

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