Regenerating hair cells in human vestibular sensory epithelia

ABSTRACT: To investigate alterations in gene expression after Ad2-ATOH1-GFP transduction of human supporting cells, we measured transcriptome changes by RNA-seq. We compared gentamicin-treated tissue (to kill the hair cells) transduced with Ad2-ATOH1-GFP (to promote hair cell production) cultured for 5 days, versus control tissues only treated with gentamicin (cultured for 2 days, 8 days and 14-18 days).

ORGANISM(S): Homo sapiens

PROVIDER: GSE109320 | GEO | 2018/07/16

REPOSITORIES: GEO