Single cell RNA-seq of long-term hematopoietic stem cells (LT-HSCs) and common myeloid progenitors (CMPs)

ABSTRACT: We aimed to reseach the differences between IL4Rα high and low expression LT-HSC/CMP,our data revealed distinct sensitivities of HSCs and common myeloid progenitors (CMPs) to IL4-induced apoptosis, and IL4Rahigh HSCs were more susceptible to unfolded protein response (UPR) and irradiation-induced apoptosis.

ORGANISM(S): Mus musculus

PROVIDER: GSE109324 | GEO | 2020/06/25

REPOSITORIES: GEO