Epidermal fatty acid binding protein prevents chemical-induced skin tumorigenesis by inhibition of SOX2 expression in keratinocytes

ABSTRACT: E-FABP expression in keratinocytes increase interferons, in particualur IFNlamda, expression, which activate P53, a critical tumor suppessor, to inhibit or prevent chemical-induced skin tumorigenesis.

ORGANISM(S): Mus musculus

PROVIDER: GSE109583 | GEO | 2018/08/30

REPOSITORIES: GEO