Genomics

Dataset Information

0

CircZKSCAN1 suppresses stemness in hepatocellular carcinoma (HCC) by competing against RNA-binding protein FMRP


ABSTRACT: We found that Quaking5 protein, a RNA splicing protein was downregulated in HCC. Collectively, this study uncovers the mechanisms underlying the regulating role of circZKSCAN1 in HCC cancer stem cells and reveals that the new discovered Qki5-circZKSCAN1-FMRP-CCAR1-Wnt signaling axis is of important therapeutic value in improving the treatment of HCC. Overall design: identify the regulating role of circZKSCAN1 in HCC

INSTRUMENT(S): Illumina HiSeq 2500 (Homo sapiens)

ORGANISM(S): Homo sapiens  

SUBMITTER: Lei Chen  

PROVIDER: GSE110048 | GEO | 2019-02-02

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
GSE110048_RIP_gene_expression.txt.gz Txt
Items per page:
1 - 1 of 1

Similar Datasets

2019-01-01 | S-EPMC6587157 | BioStudies
| PRJNA432661 | ENA
| S-EPMC2908492 | BioStudies
1000-01-01 | S-EPMC5078009 | BioStudies
2019-01-01 | S-EPMC6687293 | BioStudies
2013-01-01 | S-EPMC3775950 | BioStudies
2014-01-01 | S-EPMC4268400 | BioStudies
2011-01-01 | S-EPMC3023967 | BioStudies
2016-01-01 | S-EPMC5116651 | BioStudies
1000-01-01 | S-EPMC2441545 | BioStudies