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Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells

ABSTRACT: We determined differentially regulated gene expression profile in CD4 naïve T cells cultured in presence or absence of Th17 inducing cytokines (IL23+IL1β) and anti-CD28. We reported that CD28 costimulation induced Th17-suppressive gene signature.

ORGANISM(S): Homo sapiens

PROVIDER: GSE110097 | GEO | 2018/03/12

REPOSITORIES: GEO

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Interactomics of the RLTPR protein explain its essential role for costimulation via CD28

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