Analysis of cabazitaxel-resistant mechanism in human castration-resistant prostate cancer

ABSTRACT: To investigate cabazitaxel (CBZ) resistance in prostate cancer, we examined the changes in global gene expression before and after development of acquired CBZ resistance. Functional annotation clustering (FAC) analysis of DAVID showed cell division (GO: 0051301) and mitotic nuclear division (GO: 0007067) were the most enhanced clusters in DU145CR compared with DU145.

ORGANISM(S): Homo sapiens

PROVIDER: GSE110107 | GEO | 2018/08/01

REPOSITORIES: GEO