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Small RNA profiling from cultured cells and tissues derived from Parkinson's disease patient [small RNA-seq]

ABSTRACT: High throughput sequencing of small RNAs (mature miRNA and piRNA/piRNA-like molecules) from control- and sporadic Parkinson´s disease patient derived fibroblasts (n=15), induced pluripotent stem cells (n=26) and differentiated midbrain neurons (n=10). In parallel, cingulate gyrus samples from eight control- and eight Parkinson´s disease patients obtained from the Netherlands Brain Bank were sequenced. We found significant differences between the groups in every cell type and in tissue.

ORGANISM(S): Homo sapiens

PROVIDER: GSE110719 | GEO | 2018/10/08

REPOSITORIES: GEO

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