Genomics

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Study of sarcopenia in human muscle biopsies of elderly individuals, Hertfordshire Sarcopenia Study


ABSTRACT: Purpose: The main goal of this study is to compare skeletal muscle transcriptome profilings derived from sarcopenic versus healthy subjects. Methods: We use high coverage RNA sequencing of human skeletal muscle biopsies to analyze genome-wide transcriptional changes in human sarcopenia benchmarked to healthy elderly controls. Overall design: 28 muscle biopsies from healthy subjects, 4 muscle biopsies from sarcopenic subjects, 5 muscle biopsies from subjects with only low muscle mass, 3 muscle biopsies from subjects with only low muscle strength or low muscle function.

INSTRUMENT(S): Illumina HiSeq 2500 (Homo sapiens)

ORGANISM(S): Homo sapiens  

SUBMITTER: Jerome Feige 

PROVIDER: GSE111006 | GEO | 2019-11-14

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
GSE111006_allSamplesCounts_htseqcov1_hss_forGEO.csv.gz Csv
GSE111006_lcpmy1_hss_forGEO.csv.gz Csv
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