Dietary lipids modulate Notch signaling and influence adult intestinal development and metabolism in Drosophila

ABSTRACT: We mapped about 25 million reads per sample to the Drosophila melanogaster genome (dm6). We confirmed that sterol processing genes are selectively expressed in the posterior midgut. Modifying sterol metabolism in the diet or with Hr96 mutants resulted in significant changes in metabolism transcripts, hormones expressed in enteroendocrine cells, and Notch pathway related genes.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE111057 | GEO | 2018/09/05

REPOSITORIES: GEO