Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Methionine supplementation and radiation in mouse jejunum

ABSTRACT: Methionine supplementation exarcerbates radiation injury in the mouse jejunum

ORGANISM(S): Mus musculus

PROVIDER: GSE111558 | GEO | 2018/03/09

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Methionine supplementation and radiation in mouse jejunum

Project description:Methionine supplementation and radiation in mouse jejunum

| PRJNA437410 | ENA

RNA sequence for mammary gland of ICR mice at pregnant day 17 with supplementation of methionine (Met) alone or with methionyl-methionine (Met-Met) dipeptide.

Project description:Using RNA-seq to explore the mechanisms underlysing the effects of methionyl-methionine dipeptide (Met-Met) or free methionine (Met) supplementation in Met-restricted mice during pregnancy on mammogenesis and lactation.

2022-04-02 | GSE129224 | GEO

Effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos

Project description:Maternal nutrition exclusively during the periconceptional period can induce remarkable effects on both oocyte maturation and early embryo development, which in turn can have lifelong consequences. The objective of this study was to evaluate the effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos. Holstein cows were randomly assigned to one of two treatments differing in level of dietary methionine (1.89 Met vs. 2.43 Met % of metabolizable protein) from calving until embryo flushing. High quality preimplantation embryos from individual cows were pooled and then analyzed by RNA sequencing. A total of eight Holstein dairy cows were used in this study. Preimplantation embryos recovered from each cow were pooled in order to generate two replicates per cow assayed. Each pool consisted of 2-4 expanded blastocysts with excellent quality. Overall, a total of 16 embryo pools underwent RNA extraction, amplification, and subsequent sequencing.

2013-06-21 | E-GEOD-48147 | biostudies-arrayexpress

Effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos

2013-06-21 | GSE48147 | GEO

Maternal methionine supplementation alters the epigenome of the offspring

Project description:Maternal methionine supplementation alters the epigenome of the offspring

| PRJNA481389 | ENA

Maternal methionine supplementation alters the epigenome of the offspring [RNA-Seq]

Project description:Maternal methionine supplementation alters the epigenome of the offspring [RNA-Seq]

| PRJNA480770 | ENA

Maternal methionine supplementation alters the epigenome of the offspring [Bisulfite-Seq]

Project description:Maternal methionine supplementation alters the epigenome of the offspring [Bisulfite-Seq]

| PRJNA481390 | ENA

Folate Pathway Disruption Leads to Critical Depletion of Methionine Derivatives in Mycobacterium tuberculosis

Project description:In this study, screening efforts identified novel antifolates with potent, targeted activity against whole cell Mycobacterium tuberculosis. Liquid chromatography-mass spectrometry analysis of antifolate-treated cultures revealed unique metabolic disruption, including decreased pools of methionine and S-adenosylmethionine. Transcriptomic analysis highlighted up-regulation genes involved in the biosynthesis and utilization of methionine. Supplementation with amino acids or methionine derivatives was sufficient to rescue cultures from MIC-level antifolate treatment. Instead of the “thymineless death” that characterizes folate pathway inhibition in a wide variety of organisms, these data suggest that M. tuberculosis is vulnerable to a critical disruption of the biosynthesis of methionine-derived compounds. These arrays look at the expression profile triggered by exposure to three different anti-folates (WR99210, dimethyl and diethyl methotrexate) in three biological replicates and in a matched set of untreated samples.

2014-03-19 | E-GEOD-55979 | biostudies-arrayexpress

Maternal methionine supplementation alters the epigenome of the offspring [Bisulfite-Seq]

Project description:Maternal nutrition can induce modifications in the epigenome of the fetus, resulting in gene expression alterations and impacting future performance. Epigenetic changes are related to nutrition via the one carbon cycle, which involves aminoacid methionine. We hypothesized that an increased dietary methionine in beef cows during early gestation will impact the whole-genome DNA methylation and transcriptome of the offspring.

2018-07-17 | GSE117194 | GEO

Maternal methionine supplementation alters the epigenome of the offspring [RNA-Seq]

2018-07-13 | GSE116974 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data