Adipose derived stem cells (ASCs) methylation differences between lean and obese individuals

ABSTRACT: Pathological expansion of adipose tissue (AT) in obesity is supported by adipocyte precursors, termed adipose-derived stromal/stem cells (ASCs). Elucidation of mechanisms underlying ASC function may lead to therapeutic interventions to treat fat mass accumulation. Using epigenome-wide association studies, we explored the impact of obesity on the methylation signature of human ASCs.

ORGANISM(S): Homo sapiens

PROVIDER: GSE111632 | GEO | 2019/12/05

REPOSITORIES: GEO