Canine osteosarcoma tissues vs. normal bone

ABSTRACT: Leveraging the conserved cancer genomes across mammals has the potential to transform driver gene discovery in orphan cancers. Here, we combine cross-species genomics with validation across human-dog-mouse systems to uncover a new osteosarcoma driver genes. This widely applicable cross-species approach serves as a platform to expedite search of cancer drivers in rare human malignancies offering new targets for cancer therapy.

ORGANISM(S): Canis lupus familiaris

PROVIDER: GSE111637 | GEO | 2021/03/08

REPOSITORIES: GEO