Effect of transgenic RNAi on wandering third instar larval fat body gene expression in Drosophila melanogaster

ABSTRACT: We compared four transcription factor knockdowns using transgenic RNAi expressed in the larval fat body. FOXO, Tfb1, p53, and Stat92E-dependent gene expression in the Drosophila fat body was quantified on control and high-sugar diets in order to generate expression profiles via RNA-seq. These expression data were used to build a gene regulatory network to predict novel roles for these and other genes during caloric overload.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE111728 | GEO | 2018/03/13

REPOSITORIES: GEO