Genomics

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PIMT/NcoA6IP deletion in the mouse heart causes delayed cardiomyopathy attributable to perturbation in energy metabolism


ABSTRACT: Global gene expression analysis reveals that PIMT regulates many genes involved in energy metabolism, calcium signaling, and oxidative phosphorylation in myocardium. Overall design: RNA samples were prepared from hearts of 5 control PIMT floxed mice (PIMTfl/fl) and 5 Cre-loxP-mediated cardiomyocyte-specific deletion of PIMT (csPIMT-/-) mice. RNA were pooled and subjected to RNA-seq analysis.

INSTRUMENT(S): Illumina HiSeq 2500 (Mus musculus)

ORGANISM(S): Mus Musculus

SUBMITTER: Matthew J. Schipma  

PROVIDER: GSE111862 | GEO | 2019-01-01

REPOSITORIES: GEO

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