Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
SUBMITTER: Xingbo Mo
PROVIDER: GSE111942 | GEO | 2018-10-14
REPOSITORIES: GEO
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Zhu Hong H Wu Long-Fei LF Mo Xing-Bo XB Lu Xin X Tang Hui H Zhu Xiao-Wei XW Xia Wei W Guo Yu-Fan YF Wang Ming-Jun MJ Zeng Ke-Qin KQ Wu Jian J Qiu Ying-Hua YH Lin Xiang X Zhang Yong-Hong YH Liu Yao-Zhong YZ Yi Neng-Jun NJ Deng Fei-Yan FY Lei Shu-Feng SF
Annals of the rheumatic diseases 20181008 1
<h4>Objectives</h4>To identify novel DNA methylation sites significant for rheumatoid arthritis (RA) and comprehensively understand their underlying pathological mechanism.<h4>Methods</h4>We performed (1) genome-wide DNA methylation and mRNA expression profiling in peripheral blood mononuclear cells from RA patients and health controls; (2) correlation analysis and causal inference tests for DNA methylation and mRNA expression data; (3) differential methylation genes regulatory network construct ...[more]