Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genome-wide analysis of circRNA expression profile in non-small cell lung cancer (NSCLC) tissues and matched adjacent normal tissues

ABSTRACT: Non-small cell lung cancer (NSCLC) is a common lung disorder.Recent studies have shown that circRNA plays critical roles in a myriad of biological processes and human diseases,Since the roles of circRNA in NSCLC remain unknown,they were investigated in the study.Our findings indicate that the expression profiles of circRNAs have changed in NSCLC as compared with normal lung, and may provide novel insight into the molecular mechanism underlying the disease and potential novel diagnostic or therapeutic targets for NSCLC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE112214 | GEO | 2019/03/22

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Transcriptome of human NSCLC tissues

Project description:RNA from patient samples was isolated to examine the TGFb pathway expression between matching pairs of tumor-free lung and NSCLC specimen RNA from patient samples was isolated to examine the TGFb pathway expression between matching pairs of tumor-free lung and NSCLC specimen

2016-05-18 | E-GEOD-74706 | biostudies-arrayexpress

Genome-wide analysis of circRNA expression profile in non-small cell lung cancer (NSCLC) tissues and matched adjacent normal tissues

Project description:Genome-wide analysis of circRNA expression profile in non-small cell lung cancer (NSCLC) tissues and matched adjacent normal tissues

| PRJNA445280 | ENA

Transcriptome of human NSCLC tissues

Project description:RNA from patient samples was isolated to examine the TGFb pathway expression between matching pairs of tumor-free lung and NSCLC specimen

2016-05-18 | GSE74706 | GEO

Gene expression profiling of the adjacent airway field cancerization in early stage NSCLC

Project description:Previous work has shown that lung tumors and normal-appearing adjacent lung tissues share specific abnormalities that may be highly pertinent to the pathogenesis of lung cancer. However, the global and molecular adjacent airway field cancerization in non-small cell lung cancer (NSCLC) has not been characterized before. We sought to understand the transcriptomic architecture of the adjacent airway field canerization, in conjunction with tumors, to gain additional insights into the lung cancer biology and oncogenesis. We analyzed the transcriptome, using the Affymetrix Human Gene 1.0 ST platform, of matched NSCLC tumors, multiple normal airway epithelia with differential distance from the tumors as well as uninvolved normal lung tissues. We analyzed the airway field cancerization transcritpome to determine global differentially expressed cancerization profiles in adjacent airways as well as airway profiles that may be modulated by distance from tumors.

2014-03-04 | E-GEOD-44077 | biostudies-arrayexpress

Transcription profiling by array of human non-small cell lung cancer and normal adjacent lung tissue matched pairs

Project description:Affymetrix exon array data set (HuEx-1.0_st) derived from matched pairs of non-small cell lung cancer (NSCLC) and normal adjacent lung tissue (NAT). This data set includes both the adenocarcinoma (AdCa) as well as the squamous cell carcinoma (SCC) subtype of NSCLC.

2011-03-01 | E-MEXP-2644 | biostudies-arrayexpress

Gene expression profiling of the adjacent airway field cancerization in early stage NSCLC

2014-03-04 | GSE44077 | GEO

Genome-wide analysis of long noncoding RNA expression profile in non-alcoholic fatty liver disease

Project description:Non-alcoholic fatty liver disease (NAFLD) is a common liver disorder and affects approximately one third of the general population.Recent studies have shown that long non-coding (lncRNA) plays critical roles in a myriad of biological processes and human diseases,Since the roles of lncRNA in NAFLD remain unknown,they were investigated in the study.Our findings indicate that the expression profiles of lncRNAs has changed in NAFLD as compared with normal liver, and may provide novel insight into the molecular mechanism underlying the disease and potential novel diagnostic or therapeutic targets for NAFLD. Microarray expression profiling of mRNAs and lncRNAs were conducted using RNA extracted from five NAFLD liver tissues and five normal liver samples.

2015-09-08 | E-GEOD-72756 | biostudies-arrayexpress

CircTLCD4-RWDD3 promotes lymphatic metastasis in non-small cell lung cancer

Project description:Lung cancer is the leading cause of cancer-related death worldwide, and non-small cell lung cancer (NSCLC) accounts for approximately 85% of lung cancers. Lymphatic metastasis serves as a predominant NSCLC metastatic route and an essential predictor of patient prognosis. Recently, circular RNA (circRNA) has emerged as critical mediator in various tumor initiation and progression. To identify essential circRNA that involves in the lymphatic metastasis of NSCLC, Next generation sequencing (NSG) was performed in 6 paired NSCLC tissues and normal adjacent tissues (NAT).

2023-12-01 | GSE235634 | GEO

Genome-wide analysis of long noncoding RNA expression profile in colorectal cancer

Project description:Human colorectal cancer (CRC) is the third most common cancer in the world.Recent studies have shown that long non-coding (lncRNA) plays critical roles in a myriad of biological processes and human diseases,Since the roles of lncRNA in CRC remain largely unknown,they were investigated in the study.Our findings indicate that the expression profiles of lncRNAs has changed in CRC as compared with adjacent non-tumor samples, and may provide novel insight into the molecular mechanism underlying the disease and potential novel diagnostic or therapeutic targets for CRC.

2016-11-26 | GSE90524 | GEO

Genome-wide analysis of long noncoding RNA expression profile in non-alcoholic fatty liver disease

2015-09-08 | GSE72756 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data