Array-comparative genomic hybridization by using DualChip® human cancer 1.1 arrays

ABSTRACT: Tumors often harbor several genetic aberrations at both RNA and DNA level. Integration of expression data with copy number changes represents a powerful strategy to investigate genes involved in tumorigenesis. Here we describe a fluorescent array-based Comparative Genomic Hybridization protocol to be used on a commercial microarray platform optimized to detect cancer-related gene expression. This method will be valuable to use a single low-density array platform monitoring gene expression and copy number assessment in parallel. Keywords: Comparative genomic hybridization, neuroblastoma

ORGANISM(S): Homo sapiens

PROVIDER: GSE11225 | GEO | 2008/04/22

SECONDARY ACCESSION(S): PRJNA106835

REPOSITORIES: GEO