Impact of depletion of groucho or notch on transcription in Drosophila intestinal stem cells (ISCs).

ABSTRACT: Purpose: To analysis impacts of groucho and notch on transcription in Drosophila ISCs by mRNA-seq. Methods: mRNA-seq of RNA extracted from FACS sorted Drosophila ISCs. Results: Groucho loss in ISCs leads to disruption of lateral inhibition,and knocking down notch in ISCs down-regulates expression of e(spl) factors.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE112331 | GEO | 2019/03/15

REPOSITORIES: GEO