Expression data from mouse bone marrow late pre-B cells

ABSTRACT: B-cell development in the bone marrow proceeds through phenotypically defined stages. At the pre-B cell stage, cells stop cycling and rearrange the light chain of immunoglobulin. There are notable defects in the number of these cells and subsequent stages of B-cell development in mice with hematopoietic deficiency of the gene Ddx3x, when compared to wildtype control mice. We used microarrays to determine differences in gene expression between bone marrow pre-B cells in wild-type mice and those deficient in Ddx3x in hematopoietic cells (Vav1-cre x Ddx3x-floxed, male, hemizygous)

ORGANISM(S): Mus musculus

PROVIDER: GSE112549 | GEO | 2018/03/31

REPOSITORIES: GEO