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GSK3 inhibition Induces Glioma Cell Death through c-MYC, NF-kB and Glucose Regulation

ABSTRACT: We identified GSK3 as a regulator of GBM cell survival using microarray analysis, small molecule and genetic inhibitors of GSK3 activity. Various molecular and genetic approaches were then employed to dissect out the molecular mechanisms responsible for GSK3 inhibition-induced cytotoxicity. Keywords: time course

ORGANISM(S): Homo sapiens

PROVIDER: GSE11285 | GEO | 2009/01/01

SECONDARY ACCESSION(S): PRJNA106695

REPOSITORIES: GEO

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