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Tissue/Cell DNaseI sensitivity/hypersensitivity screening II

ABSTRACT: DNaseI hypersensitivity using DNase-array method on Affy platform overall design Per DNase-array method (Sabo et al Nature Methods 3:511,2006) PMID: 15782197 This study is part of an ongoing screening process designed to obtain high quality cell-lines/tissues for further high throughput sequencing analysis. Bed files based on hg17 genome build Keywords: genomic

ORGANISM(S): Homo sapiens

PROVIDER: GSE11298 | GEO | 2008/04/30

SECONDARY ACCESSION(S): PRJNA106719

REPOSITORIES: GEO

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Tissue/Cell DNaseI sensitivity/hypersensitivity screening

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DNaseI sensitivity/hypersensitivity Part I

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Project description:This track is produced as part of the mouse ENCODE Project. This track shows DNaseI sensitivity measured genome-wide in mouse tissues and cell lines using the Digital DNaseI methodology (see below), and DNaseI hypersensitive sites. DNaseI has long been used to map general chromatin accessibility and DNaseI hypersensitivity is a universal feature of active cis-regulatory sequences. The use of this method has led to the discovery of functional regulatory elements that include enhancers, insulators, promotors, locus control regions and novel elements. For each experiment (tissue/cell type) this track shows DNaseI sensitivity as a continuous function using sequencing tag density (Signal), and discrete loci of DNaseI sensitive zones (HotSpots) and hypersensitive sites (Peaks). For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf

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DNaseI Hypersensitivity by Digital DNaseI from ENCODE/University of Washington

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