Transcriptomics,Genomics

Dataset Information

38

Gene expression signatures for murine stromal cells from tumor-draining lymph nodes


ABSTRACT: To determine the influence of primary tumors on pre-metastatic lymph nodes, we have employed whole genome microarray expression profiling as a discovery platform to identify gene signatures of stromal cells from tumor-draining lymph nodes, compared with normal lymph nodes. We subcutaneously inoculated C57BL/6 mice with the 4T1 mammary carcinoma. Two weeks later, tumor-draining lymph nodes were dissociated and stromal cells (CD45-) were sorted. Lymph nodes stromal cells from normal mice without tumor bearing were set as controls. Overall design: Primary tumor induced gene expression in stromal cells from tumor-draining lymph nodes was measured at 2 weeks after tumor inoculation subcutaneously. Lymph nodes stromal cells from normal mice without tumor bearing were set as controls.

INSTRUMENT(S): Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version]

SUBMITTER: Yan Gu  

PROVIDER: GSE113249 | GEO | 2018-04-18

REPOSITORIES: GEO

Similar Datasets

| GSE113250 | GEO
| GSE81146 | GEO
2011-09-22 | E-GEOD-31123 | ArrayExpress
| GSE73728 | GEO
| GSE93670 | GEO
| PRJNA450551 | ENA
| PRJNA450550 | ENA
2016-09-01 | E-GEOD-72645 | ArrayExpress
| GSE98211 | GEO
2019-01-04 | E-MTAB-7427 | ArrayExpress