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Exosomal lncRNA sequencing in Atorvastatin treated and non-treated MSC-derived exosomes

ABSTRACT: In order to investigate the molecular mechanisms underlying the further enhancement of Atorvastatin pretreated MSC-derived exosomes (MSCATV-Exo) in cardiac protection, we performed lncRNA sequencing on exosomes secreted from ATV pretreated MSCs and non treated MSCs to identify differentially expressed lncRNA. We found that 450 lncRNAs were identified to be upregulated and 1332 lncRNAs downregulated (over 1.5 fold change) in MSCATV-Exo compared to MSC-Exo.

ORGANISM(S): Mus musculus

PROVIDER: GSE113570 | GEO | 2019/02/28

REPOSITORIES: GEO

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