Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

UMI-count modeling and differential expression analysis for single-cell RNA sequencing

ABSTRACT: Single cell RNA-seq of the human alveolar rhabdomyosarcoma cell line Rh41. We also inlcude a bulk RNA-seq study of unsorted and sorted cells using CD44 as a marker

ORGANISM(S): Homo sapiens

PROVIDER: GSE113660 | GEO | 2018/04/30

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

UMI-count modeling and differential expression analysis for single-cell RNA sequencing

Project description:Single cell RNA-seq of the human alveolar rhabdomyosarcoma cell line Rh41.

2019-09-13 | GSE135564 | GEO

Genome-wide binding of EHMT2 in RH41 ARMS cells.

Project description:We report the genome wide occupancy of G9a in RH41 Alveolar Rhabdomyosarcoma cell line.

2019-01-29 | GSE118666 | GEO

UMI-count modeling and differential expression analysis for single-cell RNA sequencing.

Project description: Not available

| S-EPMC5984373 | biostudies-literature

miRNA profiling of rhabdomyosarcoma-derived exosomes compared to donor cells, using the Affymetrix GeneChip miRNA 3.0 array

Project description:Exosomes were isolated by differential centrifugation from the fusion negative human embryonal rhabdomyosarcoma (ERMS) cell lines (JR1, Rh36, and RD) and fusion positive alveolar RMS (ARMS) cell lines (Rh30 and Rh41) and characterized by western blot for exosomal markers. miRNA content of the RMS-derived exosomes was determined using the Affymetrix GeneChip miRNA 3.0 array and analyzed to specify differentially deregulated (either enriched or depleted) miRNA relative to cellular miRNA from the respective ERMS and ARMS cell lines. Characterization of the miRNA content of RMS exosome is needed to better understand the mechanism by which these particles exert their physiologic effects, notably on proliferation, migration, invasion, and metastasis.

2016-12-01 | E-MTAB-5321 | biostudies-arrayexpress

Transcriptional profiling by RNA-seq in shG9a Rh41 rhabdomyosarcoma cells

Project description:Alveolar Rhabdomyosarcoma (ARMS) is the most aggressive subtype mainly caused by the expression of PAX3/7-FOXO1 oncoproteins Here, we show that G9a interacts with PAX3-FOXO1 and regulates its activity. In line with this, transcriptomic analysis by RNA-seq revealed that G9a depletion in RH41 cells induced transcriptional changes inversely correlated by those imposed by PAX3-FOXO1 expression. Overall, our results indicate that G9a promotes PAX3-FOXO1 stability, thus sustaining ARMS myoblastic state.

2022-08-22 | GSE152359 | GEO

PanCancer pathway anaysis of RH41 Human Alveolar Rhabdomyosarcoma (ARMS) cell line

Project description:PanCancer pathway anaysis of RH41 Human Alveolar Rhabdomyosarcoma (ARMS) cell line

| PRJNA486786 | ENA

Mouse Models of Alveolar/Embryonal Rhabdomyosarcoma & Spindle Cell Sarcomas

Project description:A series of conditional mouse models of embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma and spindle cell sarcoma were generated and validated for relavence to corresponding human cancers. Conditional mouse models of embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma and spindle cell sarcoma were created by activation or deletion of Pax3:Fkhr, p53, Ptch1 or Rb1 genes.

2011-02-17 | E-GEOD-22520 | biostudies-arrayexpress

UMI-count modeling and differential expression analysis for single-cell RNA sequencing

Project description:UMI-count modeling and differential expression analysis for single-cell RNA sequencing

| PRJNA453548 | ENA

UMI-count modeling and differential expression analysis for single-cell RNA sequencing

Project description:UMI-count modeling and differential expression analysis for single-cell RNA sequencing

| PRJNA559293 | ENA

Amplification in alveolar rhabdomyosarcoma

Project description:Genomic and clinical analyses of major amplification events in alveolar rhabdomyosarcoma Affymetrix SNP 50K XbaI chips were used to anaylyze 57 alveolar rhabdomyosarcoma samples and selected cases were further analyzed using Affymetrix SNP 250K StyI chips

2010-10-16 | E-GEOD-24715 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data