In vivo analysis of camptothecin effect in primary DRG neuron after sciatic nerve injury

ABSTRACT: Analysis of gene expression in injured primary DRG with or without camptothecin (CPT) treatment after sciatic nerve crushing may help us identify critical molecular pathways related to axon regeneration. We performed RNA-sequencing of (i) Naive primary DRG tissues without injury, (ii) Primary DRG tissues with vehicle treatment different time-points (18, 24, 36 hours) after sciatic nerve injury, and (iii) Primary DRG tissues with camptothecin treatment different time-points (18, 24, 36 hours) after sciatic nerve injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE113672 | GEO | 2020/07/24

REPOSITORIES: GEO