Yki- and Ras-induced intestinal stem cells (ISCs) overproliferation affects gene expression in the midgut of adult flies

ABSTRACT: Purpose: Activation of yki or Ras signaling pathways in ISCs causes overproliferation and ISC reprogramming. To gain insight into yki- and Ras-induced ISC reprogramming and gene expression, we performed a transcriptomic analysis of adult midgut with overexpression of yki-3SA or Ras1A in the ISCs.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE113728 | GEO | 2018/04/27

REPOSITORIES: GEO