Transcriptome of human white and brown adipose tissue biopsies
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2500 (Homo sapiens)
SUBMITTER: 
Tobias Fromme
PROVIDER: GSE113764 | GEO | 2018-07-06
REPOSITORIES: GEO
Dataset's files
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Publications
Postprandial Oxidative Metabolism of Human Brown Fat Indicates Thermogenesis.
U Din Mueez M Saari Teemu T Raiko Juho J Kudomi Nobu N Maurer Stefanie F SF Lahesmaa Minna M Fromme Tobias T Amri Ez-Zoubir EZ Klingenspor Martin M Solin Olof O Nuutila Pirjo P Virtanen Kirsi A KA
Cell metabolism 20180614 2
Human studies suggest that a meal elevates glucose uptake in brown adipose tissue (BAT). However, in postprandial state the thermogenic activity and the metabolism of non-esterified fatty acids (NEFAs) in BAT remain unclear. Using indirect calorimetry combined with positron emission tomography and computed tomography (PET/CT), we showed that whole-body and BAT thermogenesis (oxygen consumption) increases after the ingestion of a mixed carbohydrate-rich meal, to the same extent as in cold stress. ...[more]
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