Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells

ABSTRACT: Transcription factor Bach1 is a member of the alkaline leucine zipper protein family. Our results therefore highlight a critical role for Bach1 proteins in a regulatory network that integrates essential Wnt/β-catenin and nodal-Smad signaling to repress mesendodermal differentiation of pluripotent cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE113817 | GEO | 2019/03/28

REPOSITORIES: GEO